21120-91-2

Colorless to pale yellow liquid

1-Bromobenzocyclobutene may be used in the synthesis of following compounds:

• five-membered zirconacycles
• benzocyclobutenol and benzocyclobutenone
• 2,3-dimethoxyprotoberberinium bromide, via reaction with 3,4-dihydro-6,7-dimethoxyisoquinoline

1-Bromobenzocyclobutene is a useful synthon. It has important applications in organometallic methodology. Reaction between cycloheptatriene, bromoform, potassium carbonate and 18-crown-6 at 140°C yields 1-bromobenzocyclobutene.