2055022-35-8

Propargyl-PEG10-alcohol is a heterobifunctional PEG linker which enables Click Chemistry reactions with azide-bearing biomolecules; copper catalyst is needed. The hydrophilic PEG units increase aqueous solubility.

Propargyl-PEG9-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG9-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

PEGs

[1] Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.