2054339-01-2

N-Boc-N-bis(PEG2-acid) is a branched PEGylation reagent, it can react with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

N-Boc-N-bis(PEG2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PEGs

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005