1919044-99-7

NH-bis(PEG2-acid) HCl salt is an anqueous soluble branched compound with a central amino group and two terminal carboxylic acids. The amino group is reactive with activated NHs ester, Carboxylic group can react with primary amino groups.

NH-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PEGs

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005