2002-16-6

This product is a colorless solid, mp 66～67℃, insoluble in water, soluble in organic solvents such as benzene.

Phenylguanidine is used to prepare (4-Aminomethyl)phenylguanidine derivative, which is a nonpeptidic highly selective inhibitor of human urokinase. A series of substituted phenylguanidine compounds are selective inhibitors of urokinase.

This guanidine salt (FW = 136.18 g/mol; CAS 2002-16-6) inhibits trypsin, Ki = 72.5 μM and urokinase, or u-plasminogen activator.