1966129-74-7

Name	LYPLAL1-IN-11
CAS	1966129-74-7
Molecular Formula	C29H29N7O4
MDL Number	MFCD32197203
Molecular Weight	539.59
MOL File	1966129-74-7.mol

Synonyms

LYPLAL1-IN-1 LYPLAL1-IN-11 LYPLAL1-IN-1 (COMPOUND 11) (2R,3R)-1-(3-(4-(2-morpholinopyrimidin-5-yl)phenyl)-1H-1,2,4-triazole-1-carbonyl)-2-phenylpiperidine-3-carboxylic acid 3-Piperidinecarboxylic acid, 1-[[3-[4-[2-(4-morpholinyl)-5-pyrimidinyl]phenyl]-1H-1,2,4-triazol-1-yl]carbonyl]-2-phenyl-, (2R,3R)-

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Chemical Properties

Boiling point	824.6±75.0 °C(Predicted)
density	1.43±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
pka	3.98±0.40(Predicted)
color	White to off-white

Hazard Information

Description

LYPLAL1-IN-11 is a potent and selective covalent inhibitor of lysophospholipase-like 1 (LYPLAL1).

Uses

LYPLAL1-IN-1 (Compound 11) is an selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (LYPLAL1) with an IC50 of 0.006 μM. LYPLAL1-IN-1 increases glucose production[1].

storage

Store at -20°C

References

[1] Ahn K, et al. Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. ACS Chem Biol. 2016 Sep 16;11(9):2529-40. DOI:10.1021/acschembio.6b00266
[2] Ahn K, et al. Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. ACS Chem Biol. 2016 Sep 16;11(9):2529-40.

Supplier

cjbscvictory

Telephone13348960310 13348960310

Websitehttps://www.weikeqi-biotech.com/

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Shanghai Fengyong Biotechnology Co., Ltd.

Telephone021-10000000 13000000000

Websitehttps://www.abmole.cn

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