Store at -20°C, sealed storage, away from moisture and light
solubility
DMSO : 170 mg/mL (192.01 mM; Need ultrasonic)
form
Solid
pka
10.68±0.40(Predicted)
color
Off-white to brown
Hazard Information
Uses
dBET23 is a highly effective and selective PROTAC BRD4 degrader with a DC50/5h of ~ 50 nM for BRD4BD1 protein[1].
storage
Store at -20°C, sealed storage, away from moisture and light
References
[1] Nowak RP, et al. Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat Chem Biol. 2018;14(7):706-714. DOI:10.1038/s41589-018-0055-y
