18660-81-6

Name TETRODOTOXIN CITRATE
CAS 18660-81-6
EINECS(EC#) 689-001-0
Molecular Formula C17H25N3O15
MDL Number MFCD00210218
Molecular Weight 511.39
MOL File 18660-81-6.mol
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Chemical Properties

storage temp.  Desiccate at -20°C
solubility  Citrate Buffer (pH 4.8): 30 mg/ml (100 mM)
form  A solid
pka 8.76(at 25℃)
Water Solubility  Soluble to 100 mM in water
Stability: Unstable in Acidic solution, Unstable In Acidic Solution

Safety Data

Hazard Codes  T+
Risk Statements 
Safety Statements 
RTECS  IO1450000
Toxicity
A toxin contained in the ovary and liver of puffer fish, in the eggs of the California newt and in some other animals. It is used as a chemical tool for the study of ion channels. The s.c. LD50 in mice is 10 mg/kg. It is a toxicant of nerve and muscle by blocking sodium channels, this action causing nerve and muscle paralysis. Symptoms include weakening of voluntary muscles, respiratory failure from paralysis of the diaphragm and hypotension. There is no antidote. Therapy involves artificial respiration.

Hazard Information

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