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N-pentadecanoyl-L-Homoserine lactone is an N-acyl homoserine lactone produced by Y. pseudotuberculosis and a bacterial quorum-sensing signaling molecule.¹ It activates the LasR quorum sensing receptor of bacteria in a reporter assay.² N-pentadecanoyl-L-Homoserine lactone induces GFP production in a P. putida F117 reporter strain expressing the pKR-C12 quorum-sensing operon when used at a concentration of 0.094 nM.³

N-pentadecanoyl-L-Homoserine lactone is an N-acyl Homoserine lactone compound. N-pentadecanoyl-L-Homoserine lactone is a sensing molecule for bacterial populations[1].

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1. Ortori, C.A., Atkinson, S., Chhabra, S.R., et al. Comprehensive profiling of N-acylhomoserine lactones produced by Yersinia pseudotuberculosis using liquid chromatography coupled to hybrid quadrupole-linear ion trap mass spectrometry Anal. Bioanal. Chem. 387(2),497-511(2007).
2. Passador, L., Tucker, K.D., Guertin, K.R., et al. Functional analysis of the Pseudomonas aeruginosa autoinducer PAI J. Bacteriol. 178(20),5995-6000(1996).
3. Girard, L., Blanchet, é., Intertaglia, L., et al. Characterization of N-acyl homoserine lactones in Vibrio tasmaniensis LGP32 by a biosensor-based UHPLC-HRMS/MS method Sensors (Basel) 17(4),906(2017).