182285-29-6

Cremimycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremimycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro[1].

[1] M Igarashi, et al. Cremimycin, a novel 19-membered macrocyclic lactam antibiotic, from Streptomyces sp. J Antibiot (Tokyo). 1998 Feb;51(2):123-9.