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Off-white powder

3,4-Dihydroxybenzonitrile is mainly used to synthesize drugs containing thiazole, 2-oxazoline, imidazole, triazole and benzopyrimidine structures, such as quinazoline drugs for anticancer. In recent years, in the field of new materials, 3,4-dihydroxybenzonitrile has also been used in the synthesis of photosensitive materials.

3-Methoxy-4-hydroxybenzaldehyde (vanillin) was used as the raw material, and 3-methoxy-4-hydroxybenzonitrile was obtained by reaction with hydroxylamine hydrochloride, and then 3,4-Dihydroxybenzonitrile was synthesized by demethylation reaction with alkali metal halide. The product content was 99.8%, and the total yield based on vanillin was 75.2%.