Definition
ChEBI: Dipymetitrone is an organonitrogen heterocyclic compound that is 1H,5H-[1,4]dithiino[2,3-c:5,6-c']dipyrrole-1,3,5,7(2H,6H)-tetrone substituted at positions 2 and 6 by methyl groups. It has a role as an antifungal agrochemical. It is an organic heterotricyclic compound, a dicarboximide fungicide, an organosulfur pesticide, an organosulfur heterocyclic compound and an organonitrogen heterocyclic compound. It is functionally related to a maleimide.
Mechanism of action
Dipyridamole(16114-35-5) appears to act in vivo by synergistically modifying several biochemical pathways, including:
(1) inhibition of platelet cAMP-phosphodiesterase;
(2) potentiation of adenosine inhibition of platelet function by blocking reuptake by vascular and blood cells, and subsequent degradation of adenosine; and possibly;
(3) potentiation of PGI2 antiaggregatory activity and enhancement of PGI2 biosynthesis.
These independent processes inhibit platelet function by increasing platelet cAMP through both a reduction in enzymatic cAMP-degradation, and stimulation of cAMP formation via activation of adenylcyclase by adenosine and possibly PGI2.
Synthesis
Dipymetitrone(16114-35-5) is synthesised as follows:
The synthesis of dipymetitrone could start from the reaction of
methylamine and succinic anhydride (67) to afford 68. Treatment of 68 with thionyl chloride and
isomerization of the intermediate diisomaleimide-dithiine with water yields dipymetitrone.
Uses
Dipymetitrone(16114-35-5) is a Dicarboximide fungicide that can be used as a pesticide chemical, any substance used to control, prevent or destroy animal, microbial or plant pests. It is also used as any substance for aquaculture, horticulture, forestry, etc.
