158959-32-1

SC57666 is a selective COX2 inhibitor with an IC50 of 26 nM.

ChEBI: SC-57666 is a stilbenoid.

COX-2: 26 nM (IC₅₀)

Store at -20°C

[1] Reitz DB, et al. Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally activeCOX2 inhibitors. J Med Chem. 1994 Nov 11;37(23):3878-81. DOI:10.1021/jm00049a005
[2] Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX2 inhibitor. Br J Pharmacol. 1997 May;121(1):105-17. DOI:10.1038/sj.bjp.0701076