Dextrorphan-d
3 (tartrate) (Item No. 15810) is intended for use as an internal standard for the quantification of dextrorphan (tartrate) (Item No.
15886) by GC- or LC-MS. Dextrorphan is categorized as an arylcyclohexylamine and is a metabolite of dextromethorphan (hydrobromide hydrate) (Item No.
13950), an antitussive found in cough medicines. Dextrorphan, while also having antitussive activity, is psychoactive, leading to the abuse of cough medicines containing the parent compound.
1,2 Dextrorphan antagonizes NMDA and μ-opioid receptors (K
is = 54 and 420 nM, respectively) and inhibits norepinephrine and serotonin transporters (K
is = 340 and 401 nM, respectively).
3,4,5 This product is intended for research and forensic applications.
