Chemical Properties
solid
Uses
Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.
General Description
Crystals or fine white powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Parbendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Parbendazole emits toxic fumes.
Fire Hazard
Flash point data for Parbendazole are not available; however, Parbendazole is probably combustible.
Definition
ChEBI: N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester is a carbamate ester and a member of benzimidazoles.
Synthesis
Including acetylation, nitration, hydrolysis, reduction, ring-forming five reaction steps, p-n-butyl aniline as raw material, first acetylation with acetic anhydride, and then nitration with nitric acid, the product was poured into the ice-water mixture,
