141426-89-3

Ro 09-1679 is a thrombin inhibitor, with an IC50 of 33.6 μM. Ro 09-1679 inhibits the enzyme activities, with IC50 values of 3.3, 0.04 and 0.0346 μM for factor Xa, trypsin and papain, respectively[1].

[1] Kamiyama T, et al. Ro 09-1679, a novel thrombin inhibitor. J Antibiot (Tokyo). 1992 Mar;45(3):424-7. DOI:10.7164/antibiotics.45.424