Hazard
Flammable, dangerous fire risk.
Potential Exposure
Alert: (n-isomer): Possible risk of
forming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergic
reaction), (sec-isomer): Drug. n-Butylamine is used in
pharmaceuticals; dyestuffs, rubber, chemicals, emulsifying
agents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as a
fungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate
(a lube oil additive); as an intermediate in the production
of rubber and in rust preventatives and emulsion deterrents
in petroleum products. It is used in the manufacture of
several drugs
First aid
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if
heart action has stopped. Transfer promptly to a medical
facility. When this chemical has been swallowed, get medical attention. Rinse out mouth and do not induce vomiting.
Medical observation is recommended for 24 to 48 hours
after breathing overexposure, as pulmonary edema may be
delayed. As first aid for pulmonary edema, a doctor or
authorized paramedic may consider administering a drug or
other inhalation therapy
Shipping
UN1125 n-Butylamine, Hazard Class: 3; Labels:
3—Flammable liquid, 8—Corrosive material. UN2014
Isobutylamine, Hazard Class: 3; Labels: 3—Flammable
liquid, 8—Corrosive material
Incompatibilities
May form explosive mixture with air.
May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reacts
with strong oxidizers and acids, causing fire and explosion
hazard. Incompatible with organic anhydrides; isocyanates,
vinyl acetate; acrylates, substituted allyls; alkylene oxides;
epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in
presence of moisture. The tert-isomer will attack some
forms of plastics
Chemical Properties
Butyl amines are highly flammable, colorless
liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:
Chemical Properties
Colorless to yellow liquid; fishy ammonia aroma.
Chemical Properties
colourless liquid with an amine odour
Waste Disposal
Use a licensed professional
waste disposal service to dispose of this material. Dissolve
or mix the material with a combustible solvent and burn in
a chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed.
Definition
ChEBI: A primary aliphatic amine that is butane in which one hydrogen at position 2 is replaced by an amino group. A fumigant fungicide with a high potential for bioaccumulation, it is not approved for fungicidal use in the European Union.
Production Methods
2-Butylamine is manufactured by the condensation of methyl
ethyl ketone with ammonia–hydrogen in the presence of
Ni catalyst. It has been used as a fungistat.
Aroma threshold values
High strength odor; fishy type; recommend smelling in a 0.10% solution or less.
Health Hazard
Recommended Personal Protective Equipment: Chemical safety goggles; rubber gloves and apron; respiratory protective equipment; non-sparking shoes; Symptoms Following Exposure: Inhalation causes irritation of burns of the respiratory system; exposure to concentrated vapors can cause asphyxiation. Ingestion causes burns of mouth and stomach. Contact with eyes causes lachrymation, conjunctivitis, burns, corneal edema. Contact with skin causes irritation or burns, dermatitis; General Treatment for Exposure: INHALATION: remove patient from exposure; keep him quiet; contact physician. INGESTION: give large amount of water; induce vomiting; consult a physician. EYES: flush thoroughly with water for 15 min.; call physician immediately. SKIN: remove all contaminated clothing; flood affected area with large quantities of water; consult a physician; Toxicity by Inhalation (Threshold Limit Value): Data not available; Short-Term Exposure Limits: Data not available; Toxicity by Ingestion: Grade 3; oral LD50 = 380 mg/kg (rat); Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: Vapors are moderately irritating such that personnel will not usually tolerate moderate or high concentrations; Liquid or Solid Irritant Characteristics: Severe skin irritant. Causes second- and third-degree burns on short contact and is very injurious to the eyes; Odor Threshold: Data not available.
Chemical Reactivity
Reactivity with Water: No reaction; Reactivity with Common Materials: May corrode some metals in presence of water; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Flush with water; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Toxics Screening Level
The initial threshold screening level (ITSL) for sec-butylamine is 5 μg/m3 based on an annual averaging time.
