ChemicalBook CAS DataBase List 137-16-6

137-16-6

Name	Sodium lauroylsarcosinate
CAS	137-16-6
EINECS(EC#)	205-281-5
Molecular Formula	C15H30NNaO4
MDL Number	MFCD08273748
Molecular Weight	311.39
MOL File	137-16-6.mol

Synonyms

GARDOL LAUROYLSARCOSINE, SODIUM SALT N-DODECANOYL-N-METHYLGLYCINE SODIUM SALT N-DODECANOYLSARCOSINE SODIUM SALT HYDRATE N-DODECANOYLSARCOSINE SODIUM SALT MONOHYDRATE N-LAUROYLSARCOSINE NA-SALT N-LAUROYLSARCOSINE SODIUM SALT N-LAUROYLSARCOSINE SODIUM SALT HYDRATE N-LAURYL SARCOSINE, SODIUM SALT n-methyl-n-(1-oxododecyl)glycine sodium salt SARCOSYL SARCOSYL NL SARKOSYL SARKOSYL NL 'SARKOSYL' NL30 SARKOSYL NL-30 SODIUM LAUROYLSARCOSINATE SODIUM LAUROYL SARCOSINE SODIUM N-DODECANOYL-N-METHYLGLYCINATE SODIUM N-DODECANOYLSARCOSINATE

Chemical Properties

Appearance	white powder
Melting point	46 °C
Boiling point	350.00°C - 410.00°C
bulk density	400kg/m3
density	1.033 g/mL at 20 °C
vapor pressure	0.02 hPa (20 °C)
RTECS	MC0598960
Fp	267℃
storage temp.	room temp
solubility	H₂O: 1 M at 20 °C, clear, colorless
form	Powder
color	White
Specific Gravity	1.03 (20/4℃)
Odor	at 100.00?%. bland
PH	7.0-9.0 (25℃, 1M in H2O)
Stability:	Stable. Incompatible with strong oxidizing agents.
Water Solubility	Soluble in water (293 g/L).
Sensitive	Hygroscopic
λmax	λ: 260 nm Amax: 0.2 λ: 280 nm Amax: 0.06
Merck	4368
BRN	5322974
Cosmetics Ingredients Functions	HAIR CONDITIONING VISCOSITY CONTROLLING CLEANSING ANTISTATIC SKIN CONDITIONING SURFACTANT - EMULSIFYING SURFACTANT - CLEANSING FOAMING
InChI	1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
InChIKey	KSAVQLQVUXSOCR-UHFFFAOYSA-M
SMILES	[Na+].N(CC(=O)[O-])(C)C(=O)CCCCCCCCCCC
LogP	0.37
CAS DataBase Reference	137-16-6(CAS DataBase Reference)
EPA Substance Registry System	137-16-6(EPA Substance)

Safety Data

Symbol(GHS)	GHS05,GHS06
Signal word	Danger
Hazard statements	H315-H318-H330
Precautionary statements	P260-P264-P280-P302+P352-P304+P340+P310-P305+P351+P338
Hazard Codes	Xi
Risk Statements	R36/37/38:Irritating to eyes, respiratory system and skin . less more
Safety Statements	S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S27:Take off immediately all contaminated clothing . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . less more
RIDADR	UN 2811 6.1 / PGII
WGK Germany	3
F	3-10
TSCA	Yes
REACH Registrations	Active
HazardClass	6.1
PackingGroup	II
HS Code	34021190
Storage Class	6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 2 Inhalation Aquatic Chronic 3 Eye Dam. 1 Skin Irrit. 2 Skin Sens. 1
Toxicity	LD50 orally in Rabbit: 2888 mg/kg less more

Raw materials And Preparation Products

Hazard Information

Chemical Properties

white powder

Occurrence

Sodium Lauroyl Sarcosinate (Sodium N-lauroylsarcosinate) is a natural ingredient that is derived from coconuts. However, it can also be made synthetically.

General Description

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Flammability and Explosibility

Nonflammable

Biochem/physiol Actions

N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.

Side effects

Sodium N-lauroylsarcosinate can causes skin irritation and serious eye damage. Fatal if inhaled.

Safety Profile

Sodium Lauroyl Sarcosinate is good for skin and hair. It does not have any common side effects like skin irritation and sensitivity. Sodium Lauroyl Sarcosinate is also vegan and can be added in concentrations of up to 5% in leave-on products and 15% in rinse-off products. Further, this ingredient is non-comedogenic, so it does not clog pores or cause acne. Sodium Lauroyl Sarcosinate can be used on all skin types. However, a patch test is recommended.

Synthesis

1)Synthesis of lauryl chloride: In a dry three-necked flask equipped with a reflux condenser, add a certain amount of lauric acid, heating and melting, the temperature is controlled at 60~70e, slowly add phosphorus trichloride drop by drop with suffici

Material Safety Data Sheet(MSDS)

Questions And Answer

Spectrum Detail

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137-16-6

Chemical Properties

Safety Data

Raw materials And Preparation Products

Raw materials

Hazard Information

Chemical Properties

Occurrence

General Description

Flammability and Explosibility

Biochem/physiol Actions

Side effects

Safety Profile

Synthesis

Material Safety Data Sheet(MSDS)

Questions And Answer

Uses

Application

Spectrum Detail

Well-known Reagent Company Product Information

Supplier

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