1356905-39-9

White to Off-White Crystalline Powder

Labeled Lisinopril, an orally active angiotensin-converting enzyme (ACE) inhibitor

Labelled Lisinopril, intended for use as an internal standard for the quantification of Lisinopril by GC- or LC-mass spectrometry

Lisinopril-d₅ is intended for use as an internal standard for the quantification of lisinopril by GC- or LC-MS. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor (IC₅₀ = 1.2 nM). It reduces the formation of endothelin-1 and increases nitric oxide in human vascular endothelial cells. Lisinopril inhibits the pressor response to angiotensin I in anesthetized rats and dogs (ID₅₀s = 2.3 and 6.5 μg/kg in rat and dog, respectively).

Store at -20°C