ChemicalBook CAS DataBase List 1354745-52-0

1354745-52-0

Name	ELQ－300
CAS	1354745-52-0
Molecular Formula	C24H17ClF3NO4
MDL Number	MFCD28386233
Molecular Weight	475.84
MOL File	1354745-52-0.mol

Chemical Properties

Boiling point	551.2±50.0 °C(Predicted)
density	1.362±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: 15.62 mg/mL (32.83 mM); Water: < 0.1 mg/mL (insoluble)
form	Solid
pka	0.88±0.70(Predicted)
color	White to off-white

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Information

Supplier

Shanghai JiYi Biotechnology Co. Ltd.

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Shanghai Lollane Biological Technology Co.,Ltd.

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SPIRO PHARMA

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Shanghai YuanYe Biotechnology Co., Ltd.

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ShangHai Biochempartner Co.,Ltd

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Shanghai Chaolan Chemical Technology Center

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Fan De(Beijing) Biotechnology Co., Ltd.

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HANGZHOU CLAP TECHNOLOGY CO.,LTD

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Advanced chemblocks inc

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Beijing Jin Ming Biotechnology Co., Ltd.

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Hefei Mokai Pharmaceutical Technology Co., Ltd

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Bide Pharmatech Ltd.

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Send Inquriy

Animal Model:	6-week female CF-1 mice with P. yoelii-WT infection^[2]
Dosage:	1 and 10 mg/kg
Administration:	Oral gavage; 1 mg/kg once daily for 4-day; 10 mg/kg once daily for 1-day
Result:	Inhibited P. yoelii with ED₅₀ values of 0.04 and 0.03 mg/kg for 4-day dosing and 1-day dosing, respectively.

Animal Model:	6-week female CF-1 mice with P. yoelii-WT infection^[2]
Dosage:	10 and 20 mg/kg
Administration:	Oral gavage; 10 mg/kg once daily for 4-day; 20 mg/kg once daily for 1-day
Result:	Effectively prevented recrudescence in the 4-day dosing studies with infection mice.

1354745-52-0

Chemical Properties

Safety Data

Hazard Information

Uses

in vivo

References

Supplier