Eriocitrin is a flavonoid originally isolated from lemon peel that has antioxidant and enzyme inhibitory activity.
1,2,3,4,5 Eriocitrin inhibits lipid peroxidation in a cell-free assay when used at a concentration of 10 μM and enhances the effect of α-tocopherol (Item No.
25985) on lipid peroxidation.
2 It also decreases thiobarbituric acid reactive substances (TBARS) in rat plasma when administered at a dose of 75 μmol/kg, indicating a reduction in lipid peroxidation.
3 Eriocitrin prevents acute exercise-induced increases in TBARS, N
ε-(hexanoyl)lysine (HEL),
o,o-dityrosine (DT), and nitrotyrosine (NT; Item No.
89540) in rat liver when administered at a dose of 600 mg/kg prior to exercise.
4 It is also an inhibitor of monoamine oxidase A (MAO-A) and MAO-B (IC
50s = 86.5 and 164 μM, respectively, for human recombinant receptors).
5 
