133413-70-4

PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3].

ChEBI: PF1022A is a cyclooctadepsipeptide.

Desiccate at -20°C

[1] Dornetshuber R, et al. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44. DOI:10.1016/j.bcp.2009.01.005
[2] Sasaki T, et al. A new anthelmintic cyclodepsipeptide, PF1022A. J Antibiot (Tokyo). 1992 May;45(5):692-7. DOI:10.7164/antibiotics.45.692
[3] Nwosu U, et al. Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo. Parasitology. 2011 Aug;138(9):1193-201. DOI:10.1017/S003118201100076X