1151509-01-1

Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.t is active against the P. falciparum strain K1 and L. amazonensis promastigotes.

Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC50 of 7.9 μg/ml[1].

Plasmodium

[1] Haritakun R, et al. Butyrolactones from the fungus Aspergillus terreus BCC 4651. Chem Pharm Bull (Tokyo). 2010;58(11):1545-1548. DOI:10.1248/cpb.58.1545