ChemicalBook CAS DataBase List 1333714-43-4

1333714-43-4

Name	(Rac)-Benpyrine
CAS	1333714-43-4
Molecular Formula	C16H16N6O
Molecular Weight	308.34
MOL File	1333714-43-4.mol

Chemical Properties

Boiling point	699.1±55.0 °C(Predicted)
density	1.456±0.06 g/cm3(Predicted)
solubility	DMF: 1 mg/ml
form	A solid
pka	10.01±0.10(Predicted)
color	White to off-white

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Information

Spectrum Detail

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Animal Model:	Kunming mice (7-8 weeks) treated with bovine type II collagen and a CFA complete adjuvant^[1]
Dosage:	25 mg/kg, 50 mg/kg
Administration:	Oral gavage; daily; for 3 weeks
Result:	The inflammatory cytokines IFN-γ, IL-1β and IL-6 in the blood serum were obviously reduced, and the anti-inflammatory factor IL-10 was obviously increased.