1315329-43-1

HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells.

ChEBI: N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methylbenzamide is a member of benzamides.

B-Raf^V600E: 0.09 μM (IC₅₀, in Ba/F3 cells)

4°C, protect from light, stored under nitrogen

[1] WO 2011090738 A2