1300019-38-8

Target Protein-binding moiety 4 is a BRD4(1) inhibitor with an IC50 of 7.9 μM.

Target Protein-binding moiety 4 (compound 32) is a BRD4 (1) inhibitor with an IC50 of 7.9 μM[1].

I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1[1].

BRD4: 5.1 (pIC₅₀)

Store at -20°C

[1]. Yifei Yang, et al. Combined pharmacophore models as virtual screening protocol against BRD4(1) inhibitor. Medicinal Chemistry Research (2016), 25(4), 585-595.