A71378 is a Cholecystokinin (CCK) receptor agonist with high potency & selectivity for CCK-A receptors.
Uses
A71378 is a selectivity CCK-A receptor agonist the IC50 values of 0.4 nM, 300 nM, and 1,200 nM for the pancreatic CCK-A, cortical CCK-B, and gastrin receptor, respectively. A71378 elicits pancreatic amylase secretion (EC50 = 0.16 nM) and ileal muscle contraction (EC50 = 3.7 nM)[1].
References
[1] Lin CW, et al. A71378: a CCK agonist with high potency and selectivity for CCK-A receptors. Am J Phy DOI:10.1152/ajpgi.1990.258.4.G648
