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Jmv 176 is a CCK agonist when first given, becomes cholecystokinin antagonist after 3-4 hours.

Jmv 176 is a CCK agonist when first given and becomes a cholecystokinin antagonist after 3-4 hours[1].

[1] Gourch A, et al. A cholecystokinin agonist/antagonist according to dose and time of action: effect on food intake. Neuropeptides. 1990 Dec;17(4):187-91. DOI:10.1016/0143-4179(90)90034-v