1246303-05-8

3-dodecanoyl-NBD Cholesterol is a fluorescently-tagged cholesterol derivative with the hydrophilic NBD fluorophore attached to the hydrophilic end of cholesterol. When incorporated in the membrane bilayers, the cholesterol is in the bilayers yet the fluorophore NBD is outside. It is used to study the metabolism of cholesterol derivative.

C-12 NBD Cholesterol is a fluorescently-tagged cholesterol with the hydrophilic NBD fluorophore attached to the hydrophilic end of cholesterol, separated by a 12-carbon spacer. This allows the cholesterol to orient in membrane bilayers while the fluorescent tag is presented outside the bilayer. Fluorescently-tagged lipids have been used to study their interactions with proteins, utilization by cells and liposomes, and development of assays for lipid metabolism.