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(S)-Trichostatin A ((S)-TSA) is a HDAC6-selective inhibitor with IC50s of 9.88 nM and 11.1 nM for Zebrafish HDAC6 and Human HDAC6, respectively. (S)-Trichostatin A weakly inhibits other human HDACs[1].

hHDAC6: 11.1 nM (IC₅₀); Zebrafish HDAC6: 9.88 nM (IC₅₀); hHDAC1: 206.3 nM (IC₅₀); hHDAC2: 612.65 nM (IC₅₀); hHDAC3: 320.8 nM (IC₅₀); hHDAC4: 6341 nM (IC₅₀); hHDAC5: 6325 nM (IC₅₀); hHDAC7: 1823.5 nM (IC₅₀); hHDAC8: 312.2 nM (IC₅₀); hHDAC9: 4824 nM (IC₅₀); hHDAC10: 403.35 nM (IC₅₀); hHDAC11: 2684 nM (IC₅₀)

[1] Yasuyuki Miyake, et al. Structural insights into HDAC6 tubulin deacetylation and its selective inhibition. Nat Chem Biol. 2016 Sep;12(9):748-54. DOI:10.1038/nchembio.2140