Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin[1][2].
References
[1] Murenets NV, et al. Kafamitsin--novy? pirroléfirny? antibiotik [Kafamycin--a new pyrrol ether antibiotic]. Antibiot Med Biotekhnol. 1987 Nov;32(11):811-4. PMID:2830837 [2] Li C, et al. Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167. Chembiochem. 2009 Apr 17;10(6):1064-72. DOI:10.1002/cbic.200800822
