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Tepoxalin is non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties approved for veterinary use. It has inhibitory effect on cyclooxygenase and 5-lipxygenase activity a s well as inhibiting the production of cytokines in peripheral cells outside the CNS.

ChEBI: A hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the contr l of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs.

Tepoxalin is indicated for the treatment of pain and inflammation associated with osteoarthritis in dogs. Because of the drug’s inhibitory effects on leukotrienes, there is interest in seeing if it would be beneficial in the adjunctive treatment of allergic conditions in dogs.