ChemicalBook CAS DataBase List 1000023-04-0

1000023-04-0

Name	Voruciclib
CAS	1000023-04-0
Molecular Formula	C22H19ClF3NO5
Molecular Weight	469.84
MOL File	1000023-04-0.mol

Chemical Properties

Boiling point	587.6±50.0 °C(Predicted)
density	1.493±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: soluble
form	A crystalline solid
pka	6.36±0.40(Predicted)
color	Light yellow to yellow

Safety Data

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

Hazard Information

Spectrum Detail

Supplier

Shanghai Boyle Chemical Co., Ltd.

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Chembest Research Laboratories Limited

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Bide Pharmatech Ltd.

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ShangHai Biochempartner Co.,Ltd

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Shanghai Chaolan Chemical Technology Center

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Chemleader Biomedical Co., Limited.

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Twochem Co.Ltd.

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Shanghai Hongye Biotechnology Co. Ltd

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Aishilun biotechnology (Shanghai) co., LTD

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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

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Zhejiang J&C Biological Technology Co.,Limited

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HANGZHOU CLAP TECHNOLOGY CO.,LTD

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Chunchuang (Wuhan) Technology Co., Ltd

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Animal Model:	ABC subtypes (U2932, RIVA, OCI-LY10), GCB subtypes (SU-DHL-4, NU-DHL-1) xenografted in Female NOD.CB17-Prkdcscid/NCrHsd mice
Dosage:	200 mpk
Administration:	Oral gavage; U2932, RIVA, SU-DHL-4 (six days per week for 4 weeks), OCI-LY10 (six days per week for 2 weeks), NU-DHL-1 (five days per week for 3 weeks)
Result:	Enhanced tumor growth inhibition in U2932, RIVA, SU-DHL-4 and NU-DHL-1 models except in OCI-LY10 model.

1000023-04-0

Chemical Properties

Safety Data

Hazard Information

Uses

in vivo

IC 50

storage

Spectrum Detail

Supplier

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