N-Phenylhydroxylamine is a useful synthetic intermediate. It was used as a reagent to prepare 6-halo-2-amino-3-formylchromones as potential topoisomerase inhibitor anticancer agents. It was also used in the synthesis of N-(chlorophenyl)cycloalkyl-hydroxamic acids and N-phenyl-N-hydroxycyclohexylacetamide with anti-viral activities.