Ertapenem Disodium

$32 - $1233

Product nameErtapenem Disodium
Cas No153832-38-3
MFC22H26N3NaO7S
MW499.51
MDL NumberMFCD00922233

Synonyms

1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid;ErtapeneM SodiuM(crude);disodium (4R,5R,6S)-3-[(3S,5S)-5-[(3-carboxylatophenyl)carbamoyl]pyrro lidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2 .0]hept-2-ene-2-carboxylate;Ertapenem disodium;Ertapenem Disodium (85%);Ertapenem (sodium salt);Ertapenam disodium;Ertapenem Disodium 90%

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Price

16 prices

Brand less more

Cayman Chemical Chemenu Crysdot AccelPharmtech TRC Biorbyt Ltd ApexBio Technology American Custom Chemicals Corporation Labseeker
Package less more

1mg 5mg 10mg 25mg 100mg 250mg 950mg 1g 25g

Clear All Done

Brand	Packaging	Price	Product name
AccelPharmtech AT7169	950MG	$120	ErtapenemDisodium
American Custom Chemicals Corporation API0019498	100MG	$407.4	ERTAPENEM DISODIUM
ApexBio Technology C3451	10mg	$163	Ertapenem(sodiumsalt)
ApexBio Technology C3451	5mg	$95	Ertapenem(sodiumsalt)
ApexBio Technology C3451	25mg	$339	Ertapenem(sodiumsalt)
Biorbyt Ltd orb134781	1g	$1208.7	Ertapenem Sodium
Biorbyt Ltd orb134781	100mg	$414.8	Ertapenem Sodium
Biorbyt Ltd orb134781	250mg	$615.4	Ertapenem Sodium
Cayman Chemical 20523	5mg	$109	Ertapenem (sodium salt)
Cayman Chemical 20523	10mg	$184	Ertapenem (sodium salt)

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Properties

Melting point	230-234°C (dec.)
storage temp.	Sealed in dry,2-8°C
solubility	Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Off-White
Stability	Unstable at room temperature!

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H315：Causes skin irritation

H319：Causes serious eye irritation

Precautionary statements

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313：IF SKIN irritation occurs: Get medical advice/attention.

P337+P313：IF eye irritation persists: Get medical advice/attention.

P362：Take off contaminated clothing and wash before reuse.

Description

Ertapenem sodium was introduced in the US as a once daily intravenous or intramuscular injection for the treatment of adult patients with moderate to severe bacterial infections. This new I-β-methyl carbapenem can be assembled from commercially available 4-nitrobenzyl protected β-methyl carbapenem enolphosphate and the appropriate thiol derivative. The last intermediate can be synthesized from a suitably N-protected 4- hydroxy proline derivative in a one pot operation involving bis activation of the carboxy and hydroxy groups, reaction with sodium sulfide yielding the corresponding thiolactone, aminolysis with 2-aminobenzoic acid and Kdeprotection. This bacterial cell wall synthesis inhibitor has broad spectrum antimicrobial activity including common Gram-positive and Gram-negative aerobic pathogens and restricted activity against nosocomial pathogens such as Pseudomonas aeruginosa, Acinetobacfer species, methicillin-resistant staphylococci and enterococci. Ertapenem is resistant to a broad and extended spectrum of β-lactamases (excluding metallo-beta-lactamase) and is also more resistant than imipenem to human renal dehydroxypeptidase-I-inactivation (DHP-I). In drug-resistant strains of P. aeruginosa, resistance to ertapenem and imipenem was common but almost all strains remain susceptible to at least one antipseudomal agent. In phase III studies, ertapenem showed efficacy in the treatment of obstetric and gyneacological infections, skin and soft tissues infections, community-acquired pneumonia, urinary tract infections and in intra abdominal infections. Ertapenem has improved pharmacokinetics over currently available carbapenems and cephalosporins with an extended serum half-life of 4h. The overall safety and tolerability profile of ertapenem was comparable to that seen with comparator antibacterials.

Related product price

Ertapenem $59-2379 Doripenem $39-375 153773-82-1 $12-625

Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd

$0.00/25KG

Ertapenem Disodium

CAS:153832-38-3
career henan chemical co

$1.00/1KG

disodium (4R,5R,6S)-3-[(3S,5S)-5-[(3-carboxylatophenyl)carbamoyl]pyrro lidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2 .0]hept-2-ene-2-carboxylate

CAS:153832-38-3
Hebei Guanlang Biotechnology Co., Ltd.

$10.00/1KG

Ertapenem Disodium

CAS:153832-38-3
Shaanxi Dideu Medichem Co. Ltd

$1.00/1g

Ertapenem Disodium

CAS:153832-38-3
Xiamen AmoyChem Co., Ltd
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
SIMAGCHEM CORP
AFINE CHEMICALS LIMITED
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.

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