Cefotaxime

$50 - $1666

Product nameCefotaxime
Cas No63527-52-6
MFC16H17N5O7S2
MW455.47
EINECS264-299-1
MDL NumberMFCD00864971

Synonyms

Cefotaxime;Cefotaxima acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-;Cefabol;Cephotaxime;(((2-amino- 4-thiazolyl)methoxyimino)acetyl)amino)-8-oxo-, (6r-(6alpha,7beta(z) 3-[(Acetyloxy)methyl]-7-[[(2-amino-4-thiazoly)(methoxyimino)acethyl]amino]-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid(sodium salt);(6R)-3-(Acetoxymethyl)-7α-[[(2-amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-7α-[2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxyimino]acetylamino]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

show less show more

Price

15 prices

Brand less more

Sigma-Aldrich AHH TRC ApexBio Technology Matrix Scientific AK Scientific ChemScene
Package less more

1mg 20mg 25mg 100mg y0000420 250mg 500mg 1g 2.5g 5g

Clear All Done

Brand	Packaging	Price	Product name
AHH MT-49079	5g	$310	Cefotaxime
AK Scientific J90010	1g	$60	Cefotaxime
AK Scientific F941	25mg	$98.6	Cefotaxime
AK Scientific J90010	5g	$150	Cefotaxime
ApexBio Technology BA1012	500mg	$121	Cefotaxime
ApexBio Technology BA1012	250mg	$90	Cefotaxime
ApexBio Technology SL1043	1mg	$507	Cefotaxime-d3
ChemScene CS-0013515	100mg	$50	Cefotaxime
ChemScene CS-0013515	250mg	$100	Cefotaxime
ChemScene CS-0013515	500mg	$135	Cefotaxime

1of2

Properties

Melting point	>158°C (dec.)
Density	1.80±0.1 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
pka	pKa 2.1 (H2O t=20.0 I<0.005 ) (Uncertain);3.4(H2O t=20.0 I<0.005 ) (Uncertain);10.9(H2O t=20.0 I<0.005 ) (Uncertain)
form	Solid
color	White to Off-White
Stability	Hygroscopic
Major Application	pharmaceutical (small molecule)
InChIKey	GPRBEKHLDVQUJE-QSWIMTSFSA-N
SMILES	N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(COC(C)=O)=C2C(O)=O
LogP	1.2
CAS DataBase Reference	63527-52-6(CAS DataBase Reference)
EPA Substance Registry System	5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)- (63527-52-6)

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H317：May cause an allergic skin reaction

H334：May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P284：Wear respiratory protection.

P304+P340：IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P342+P311：IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Like other third-generation cephalosporins, it has excellent anti-Gram-negative activity and is useful institutionally. It has a metabolically vulnerable acetoxy group attached to C-3 and loses approximately 90% of its activity when this is hydrolyzed. This metabolic feature also complicates the pharmacokinetic data, because both active forms are present and have different properties. Cefotaxime should be protected from heat and light and may color slightly without significant loss of potency. Like other third-generation cephalosporins, cefotaxime has less activity against staphylococci but has greater activity against Gram-negative organisms.

Related product price

Thioacetamide $9-1400 Cefotaxime sodium $8-1960 Acetamide $13-950

Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

$2.70/1kg

Cefotaxime

CAS:63527-52-6
Shaanxi TNJONE Pharmaceutical Co., Ltd

$0.00/1kg

Cefotaxime

CAS:63527-52-6
Shaanxi Xianhe Biotech Co., Ltd

$0.00/1kg

Cefotaxime

CAS:63527-52-6
career henan chemical co

$7.00/1KG

Cefotaxime

CAS:63527-52-6
TargetMol Chemicals Inc.

$30.00/50mg

Cefotaxime

CAS:63527-52-6
Henan Tianfu Chemical Co.,Ltd.
HubeiwidelychemicaltechnologyCo.,Ltd
BOC Sciences
SIMAGCHEM CORP
Hefei TNJ Chemical Industry Co.,Ltd.

More related product prices

Thioacetamide
Cefotaxime sodium
Acetamide
4-Acetamidophenol
DIACETAMIDE

Ceftiofur
153-61-7
Ceftiofur sodium
Cephalothin
116856-18-9

N,N-Dimethylacetamide
Cefpodoxime
Ceftizoxime
7-Aminocephalosporanic acid
Hydroxymethyl-7-Aminocephalosporanic acid

Cefetamet hydrochloride
Cefotaxime

1of4

Send Inquriy