Cefotaxime

$10 - $2475

Product nameCefotaxime
Cas No63527-52-6
MFC16H17N5O7S2
MW455.47
EINECS264-299-1
MDL NumberMFCD00864971

Synonyms

Cefotaxime;Cefotaxima acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-;Cefabol;(6R)-3-(Acetoxymethyl)-7α-[[(2-amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-7α-[2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxyimino]acetylamino]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Zariviz;(6R,7R)-3-[(acetyloxy)Methyl]-7-[(2E)-2-(2-aMino-1,3-thiazol-4-yl)-2-(MethoxyiMino)acetaMido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

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Price

32 prices

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aablocks Arctom AK Scientific ChemScene ApexBio Technology Sigma-Aldrich TRC Biosynth AHH Usbiological Matrix Scientific
Package less more

1mg 5mg 20mg 25mg 100mg 250mg 500mg 1g 2.5g 5g 10g 10mm*1mlindmso(solid+solvent) 25g y0000420 50g 100g 10mm*1mlindmso(solution)

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Brand	Packaging	Price	Product name
aablocks AA01DGJB	100mg	$10	Cefotaxime
AHH MT-49079	5g	$310	Cefotaxime
AK Scientific F941	100mg	$308	Cefotaxime
AK Scientific J90010	5g	$543	Cefotaxime
AK Scientific F941	5mg	$48	Cefotaxime
AK Scientific J90010	250mg	$87	Cefotaxime
AK Scientific F941	25mg	$102	Cefotaxime
AK Scientific J90010	1g	$247	Cefotaxime
ApexBio Technology BA1012	500mg	$121	Cefotaxime
ApexBio Technology BA1012	250mg	$90	Cefotaxime

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Properties

Melting point	>158°C (dec.)
Density	1.80±0.1 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
pka	pKa 2.1 (H2O t=20.0 I<0.005 ) (Uncertain);3.4(H2O t=20.0 I<0.005 ) (Uncertain);10.9(H2O t=20.0 I<0.005 ) (Uncertain)
form	Solid
color	White to Off-White
Stability	Hygroscopic
Major Application	pharmaceutical (small molecule)
InChIKey	GPRBEKHLDVQUJE-QSWIMTSFSA-N
SMILES	N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(COC(C)=O)=C2C(O)=O
LogP	1.2
CAS DataBase Reference	63527-52-6(CAS DataBase Reference)
EPA Substance Registry System	5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)- (63527-52-6)

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H317：May cause an allergic skin reaction

H334：May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P284：Wear respiratory protection.

P304+P340：IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P342+P311：IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Like other third-generation cephalosporins, it has excellent anti-Gram-negative activity and is useful institutionally. It has a metabolically vulnerable acetoxy group attached to C-3 and loses approximately 90% of its activity when this is hydrolyzed. This metabolic feature also complicates the pharmacokinetic data, because both active forms are present and have different properties. Cefotaxime should be protected from heat and light and may color slightly without significant loss of potency. Like other third-generation cephalosporins, cefotaxime has less activity against staphylococci but has greater activity against Gram-negative organisms.

Related product price

Thioacetamide $6.35-2381 Cefotaxime sodium $8-8004.25 Acetamide $6.35-1713.25

Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

$2.70

Cefotaxime

CAS:63527-52-6
Shaanxi TNJONE Pharmaceutical Co., Ltd

Cefotaxime

CAS:63527-52-6
Shaanxi Xianhe Biotech Co., Ltd

Cefotaxime

CAS:63527-52-6
career henan chemical co

$7.00

Cefotaxime

CAS:63527-52-6
TargetMol Chemicals Inc.

$30.00

Cefotaxime

CAS:63527-52-6
Henan Tianfu Chemical Co.,Ltd.
HubeiwidelychemicaltechnologyCo.,Ltd
BOC Sciences
SIMAGCHEM CORP
Hefei TNJ Chemical Industry Co.,Ltd.

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