Avacopan

$42 - $1437.11

Product nameAvacopan
Cas No112093-28-4
MFC25H27NO2
MW373.49

Synonyms

(Z)-4-Hydroxy-N-desmethyl Tamoxifen;4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol;Endoxifen;Phenol, 4-[(1Z)-1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-butenyl]-;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) see D292043;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) ;(Z)-4-Hydroxy-N-DesMethyl TaMoxifen (Endoxifen);(Z)-Endoxifen

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Price

26 prices

Brand less more

Crysdot Tocris TRC Usbiological ApexBio Technology AK Scientific Axon Medchem ChemScene American Custom Chemicals Corporation Biosynth Carbosynth
Package less more

50 0.5mg 1mg 5mg 25mg 2mg 10mg 100mg 50mg 10

Clear All Done

Brand	Packaging	Price	Product name
AK Scientific X5886	10mg	$280	N-Desmethyl-4-hydroxytamoxifen,(mixtureofisomers)
American Custom Chemicals Corporation API0010318	10MG	$794.36	(Z)-ENDOXIFEN
American Custom Chemicals Corporation API0010318	50MG	$1437.11	(Z)-ENDOXIFEN
ApexBio Technology B7481	50mg	$245	Endoxifen
ApexBio Technology B7481	50mg	$245	Endoxifen
ApexBio Technology B7481	10mg	$75	Endoxifen
ApexBio Technology B7481	10mg	$75	Endoxifen
Axon Medchem Axon2190	10mg	$137.5	Endoxifen
Axon Medchem Axon2221	5mg	$165	(Z)-Endoxifen
Axon Medchem Axon2190	50mg	$495	Endoxifen

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Properties

Melting point	127-129°C
Boiling point	519.3±50.0 °C(Predicted)
Density	1.099±0.06 g/cm3(Predicted)
storage temp.	Amber Vial, -86°C Freezer, Under Inert Atmosphere
solubility	DMSO : 50 mg/mL (133.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form	Powder
pka	10.36±0.15(Predicted)
color	White to off-white
Stability	Light Sensitive, Temperature Sensitive
InChI	InChI=1S/C25H27NO2/c1-3-24(19-7-5-4-6-8-19)25(20-9-13-22(27)14-10-20)21-11-15-23(16-12-21)28-18-17-26-2/h4-16,26-27H,3,17-18H2,1-2H3/b25-24-
InChIKey	MHJBZVSGOZTKRH-IZHYLOQSSA-N
SMILES	C1(O)=CC=C(/C(/C2=CC=C(OCCNC)C=C2)=C(/C2=CC=CC=C2)\CC)C=C1

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H302：Harmful if swallowed

H361：Suspected of damaging fertility or the unborn child

H372：Causes damage to organs through prolonged or repeated exposure

H410：Very toxic to aquatic life with long lasting effects

Precautionary statements

P201：Obtain special instructions before use.

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331：IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P312：Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Tamoxifen (TMX; ) is a selective estrogen receptor (ER) modulator used as adjuvant therapy for estrogen-dependent breast cancer. Endoxifen is an active metabolite of TMX, produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for ERs than TMX. As the efficient conversion of TMX to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.

Related product price

4-HYDROXYTAMOXIFEN $34-4725 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine $289-3200 (E)-4-Acetoxy Tamoxifen $100-496.97

Suppliers and manufacturers

Shaanxi Dideu Medichem Co. Ltd

$0.00/1KG

Endoxifen

CAS:112093-28-4
career henan chemical co

$3.00/1KG

Endoxifen

CAS:112093-28-4
TargetMol Chemicals Inc.

$30.00/1mg

Endoxifen (Z-isomer)

CAS:112093-28-4
Jiangxi Huihe Chemical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
HANGZHOU CLAP TECHNOLOGY CO.,LTD
ANHUI WITOP BIOTECH CO., LTD
Finetech Industry Limited
Zhejiang J&C Biological Technology Co.,Limited

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