(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene (contain up to 10% E-isomer)
Usbiological
469051
100mg
$468
(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene (contain up to 10% E-isomer)
Properties
Melting point
119-121°C
storage temp.
Refrigerator
solubility
Chloroform (Slightly), Methanol (Slightly)
form
Solid
color
White to Off-White
Description
A metabolite of Tamoxifen, that can be biotransformed to a quinone methide, which has the potential to alkylate DNA and may contribute to the genotoxic effects of tamoxifen. This compound slightly increases intracellular free calcium [Ca2+]i in human platelets and partially inhibits thrombin-induced [Ca2+]i elevation.
