Avacopan

$42 - $3894

Product nameAvacopan
Cas No112093-28-4
MFC25H27NO2
MW373.49

Synonyms

(Z)-4-Hydroxy-N-desmethyl Tamoxifen;4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol;Phenol, 4-[(1Z)-1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-butenyl]-;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) see D292043;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) ;(Z)-4-Hydroxy-N-DesMethyl TaMoxifen (Endoxifen);Endoxifen (Z-isomer);Avacopan

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Price

54 prices

Brand less more

Crysdot aablocks ApexBio Technology Biosynth ChemScene Axon Medchem TRC ACHEMBLOCK Tocris AK Scientific Usbiological DC Chemicals American Custom Chemicals Corporation
Package less more

0.1g 100mg 250mg 0.25g 0.5g 1g 2g 50 0.5mg 1mg 2mg 5mg 10 10mg 25mg 50mg

Clear All Done

Brand	Packaging	Price	Product name
aablocks AA007UN2	1mg	$44	Endoxifen Z-isomer
aablocks AA007UN2	5mg	$72	Endoxifen Z-isomer
aablocks AA007UN2	10mg	$88	Endoxifen Z-isomer
aablocks AA007UN2	25mg	$164	Endoxifen Z-isomer
aablocks AA007UN2	50mg	$251	Endoxifen Z-isomer
ACHEMBLOCK X203753	100MG	$350	Endoxifen
ACHEMBLOCK X203753	25MG	$200	Endoxifen
ACHEMBLOCK X203753	250MG	$700	Endoxifen
ACHEMBLOCK X203753	1G	$1550	Endoxifen
AK Scientific X5886	10mg	$280	N-Desmethyl-4-hydroxytamoxifen,(mixtureofisomers)

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Properties

Melting point	127-129°C
Boiling point	519.3±50.0 °C(Predicted)
Density	1.099±0.06 g/cm3(Predicted)
storage temp.	Amber Vial, -86°C Freezer, Under Inert Atmosphere
solubility	DMSO : 50 mg/mL (133.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form	Powder
pka	10.36±0.15(Predicted)
color	White to off-white
Stability	Light Sensitive, Temperature Sensitive
InChI	InChI=1S/C25H27NO2/c1-3-24(19-7-5-4-6-8-19)25(20-9-13-22(27)14-10-20)21-11-15-23(16-12-21)28-18-17-26-2/h4-16,26-27H,3,17-18H2,1-2H3/b25-24-
InChIKey	MHJBZVSGOZTKRH-IZHYLOQSSA-N
SMILES	C1(O)=CC=C(/C(/C2=CC=C(OCCNC)C=C2)=C(/C2=CC=CC=C2)\CC)C=C1

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H302：Harmful if swallowed

H361：Suspected of damaging fertility or the unborn child

H372：Causes damage to organs through prolonged or repeated exposure

H410：Very toxic to aquatic life with long lasting effects

Precautionary statements

P201：Obtain special instructions before use.

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331：IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P312：Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Tamoxifen (TMX; ) is a selective estrogen receptor (ER) modulator used as adjuvant therapy for estrogen-dependent breast cancer. Endoxifen is an active metabolite of TMX, produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for ERs than TMX. As the efficient conversion of TMX to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.

Related product price

4-HYDROXYTAMOXIFEN $34-4725 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine $289-3200 (E)-4-Acetoxy Tamoxifen $100-496.97

Suppliers and manufacturers

Shaanxi Dideu Medichem Co. Ltd

Endoxifen

CAS:112093-28-4
career henan chemical co

$3.00

Endoxifen

CAS:112093-28-4
TargetMol Chemicals Inc.

$30.00

Endoxifen (Z-isomer)

CAS:112093-28-4
Jiangxi Huihe Chemical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
HANGZHOU CLAP TECHNOLOGY CO.,LTD
ANHUI WITOP BIOTECH CO., LTD
Finetech Industry Limited

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