5-OXO-6E,8Z,11Z,14Z-EICOSATETRAENOIC ACID;5-OXOETE;5-KETE;5-KETOEICOSA-6E,8Z,11,Z14Z-TETRAENOIC ACID;5-Oxo-(6E,8Z,11Z,14Z)-6,8,11,14-eicosatetraenoicacid;5-OxoETE Lipid Maps MS Standard;MEASLHGILYBXFO-XTDASVJISA-N;5-OxoETE MaxSpec Standard
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase. It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils via a specific G protein-coupled receptor.
