Contains four deuterium atoms at the 3, 3', 4, and 4' positions. Intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGF2α by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGF2α is the first prominent plasma metabolite of PGF2α in the 15-hydroxy PGDH pathway. Measurement of 13,14-dihydro-15-keto PGF2α in plasma can be used as a marker of the in vivo production of PGF2α.