JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor ligand. It binds to the CB1 receptor with high-affinity (IC50 = 7.8-42 nM). The effects of JWH 200 in locomotor activity, tail-flick latency, hypothermia and ring-immobility tests are comparable or superior to Δ9-THC or WIN 55,212. It potently inhibits the contraction of electrically-stimulated murine vas deferens (IC50 = 3.7-6.0 nM).
![[1-[2-(4-Morpholinyl)ethyl]-1H-indol-3-yl]-1-naphthalenylmethanone](https://www.chemicalbook.com/CAS/GIF/103610-04-4.gif)