Карбетоцин

Использование

Carbetocin is an obstetric drug used to control postpartum hemorrhaging.
A new synthetic analog of oxytocin, carbetocin, is long acting and also has a rapid onset of action. It is an oxytocin receptor agonist and also stimulates milk let down due to its action on oxytocin receptors of myoepithelial cells.

Определение

ChEBI: Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue o oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.

Биохимия/физиол Действия

Carbetocin is a potent agonist of the oxytocin receptor, with improved in vivo stability over oxytocin.