L-5-гидрокситриптофан

Химические свойства

white to pale grey powder

Использование

A labelled metabolite of Tryptophan

Общее описание

Colorless to pale pink crystals.

Реакции воздуха и воды

L-5-Hydroxytryptophan is sensitive to air. Slightly water soluble .

Профиль реактивности

L-5-Hydroxytryptophan reacts with bases. .

Пожароопасность

Flash point data for L-5-Hydroxytryptophan are not available, however, L-5-Hydroxytryptophan is probably combustible.

Торговое название

Levothym (Promonta Lundbeck, Germany), Lévotonine (Panpharma, France), Oxyfan (Coli, Italy), Tript-OH (Sigma- Tai, Italy).

Методы очистки

Likely impurities are 5-hydroxy-D-tryptophan and 5-benzyloxytryptophan. Crystallise 5-hydroxy-L-tryptophan under nitrogen from water by adding EtOH. Store it under nitrogen. Also dissolve it in the minimum volume of hot H2O (~0.7g in 4mL) under nitrogen (charcoal) and allowed it to crystallise at 5o. The picrolonate crystallises from H2O with m 184-186o(dec). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2732-2737 1961, Morris & Armstrong J Org Chem 22 306 1957, Beilstein 22/14 V 278.]