GSK 2334470
- русский язык имя
- английское имяGSK 2334470
- CAS №1227911-45-6
- CBNumberCB62596521
- ФормулаC25H34N8O
- мольный вес462.59
- номер MDLMFCD21608525
- файл Mol1227911-45-6.mol
химическое свойство
| плотность | 1.30±0.1 g/cm3(Predicted) |
| температура хранения | 2-8°C |
| растворимость | DMSO: ≥10mg/mL |
| пка | 12.84±0.40(Predicted) |
| форма | powder |
| цвет | white to light brown |
| Стабильность | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| FDA UNII | QB5BF4GJ87 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
GSK 2334470 химические свойства, назначение, производство
Использование
GSK2334470 has been used as an inhibitor of 3-phosphoinositide dependent protein kinase-1 (PDK-1) in:- Treg cells, to identify regulators of interleukin 2 (IL-2)– signal transducer and activator of transcription 5 (STAT5) signaling
- glycodelin-transfected HEC-1B human endometrial adenocarcinoma cells.
- HeLa and Hs578T cells to test its effect on formylglycinamidine ribonucleotide synthase?(FGAMS) assembly
Биохимия/физиол Действия
GSK2334470 (GSK-470) mediates cell cycle arrest. It also inhibits cellular proliferation and induces apoptosis in cancer cells.GSK 2334470 поставщик
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