Имино (амино) метансульфоновая кислота

Описание

AMinoiMinoMethanesulfonic Acid is a parent compound and its derivatives guanylate amines; some derivatives give triazoles with azide and  aminoiminoethanenitriles with cyanide as nucleophile.

Химические свойства

White Solid

Использование

AMinoiMinoMethanesulfonic Acid can be used to prepare Guanidine derivatives.

Подготовка

Preparative Methods of AMinoiMinoMethanesulfonic Acid: by the oxidation of thiourea or aminoiminomethanesulfinic acid  (formamidinesulfinic acid) with Peracetic Acid. Many substituted aminoiminomethanesulfonic acids can  be prepared in the same way. Others have utilized Hydrogen Peroxide with sodium molybdate as a  catalyst to oxidize the corresponding thioureas to a variety of monosubstituted aminoiminomethanesulfonic acids; the substituents include phenyl, 2-methylphenyl, 4-fluorophenyl, n-propyl, cyclohexylmethyl, S-α- methylbenzyl, cyclooctyl, and benzhydryl.

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AMinoiMinoMethanesulfonic Acid is stable for at least a few weeks at room temperature. After drying, it  remains stable for at least 5 months if kept in a freezer. Thiourea and its metabolites (probably oxidized  thiourea) are tumorigenic and cause lung edema. All direct contact with the compound should be avoided;  for example, a dust mask should be worn. All residues should be destroyed with strong bleach solution.  Many substituted thioureas and their metabolites are also biologically active. Use in a fume hood.