Tosufloxacin

Имя бренда

Tosufloxacin Tosilate is JAN.

Фармацевтические приложения

It is active against a wide range of Gram-positive and Gram-negative bacteria, including Acinetobacter spp., L. pneumophila and Campylobacter spp. Unlike many quinolones it is moderately active against L. monocytogenes. C. trachomatis is also moderately susceptible. It is active against some anaerobes, including the B. fragilis group. Activity against Mycobacterium spp. is limited. It is well absorbed by the oral route, achieving a plasma concentration of c. 1 mg/L 4 h after a 300 mg dose. Around 30–35% of the dose is eliminated in the urine, with an apparent elimination half-life of 6–7 h.
Clinical experience is limited, but high clinical and bacteriological cure rates have been obtained in patients with skin and soft-tissue infections.