Oleoyl-L-α-lysophosphatidic acid sodium salt
- английское имя1-Oleoyl lysophosphatidic acid sodium salt
- CAS №22556-62-3
- CBNumberCB4454401
- ФормулаC21H42NaO7P
- мольный вес460.52
- номер MDLMFCD00142682
- файл Mol22556-62-3.mol
химическое свойство
| температура хранения | -20°C |
| форма | solid |
| цвет | white |
| Растворимость в воде | Soluble in water up to 5mg/ml with sonication |
| Чувствительный | Light & Air Sensitive & Hygroscopic |
Oleoyl-L-α-lysophosphatidic acid sodium salt химические свойства, назначение, производство
Использование
Oleoyl-L-α-lysophosphatidic Acid reduces the organ injury caused by endotoxemia in the rat.?It may be useful in the treatment of shock of various etiologies.Общее описание
Lysophosphatidic acid (LPA) is an essential metabolite for membrane biosynthesis. LPA interacts with the G protein-coupled receptors (GPCRs), called the LPA receptor and mediates signaling. Oleoyl-L-α-lysophosphatidic acid activates the receptor LPA4. In keratinocytes, oleoyl-L-α-lysophosphatidic acid promotes growth to some extent.Биохимия/физиол Действия
Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells.Oleoyl-L-α-lysophosphatidic acid sodium salt поставщик
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