Эноцитабин
- английское имяEnocitabine
- CAS №55726-47-1
- CBNumberCB3266605
- ФормулаC31H55N3O6
- мольный вес565.78
- EINECS1312995-182-4
- номер MDLMFCD00866294
- файл Mol55726-47-1.mol
химическое свойство
| Температура плавления | 141-142°C |
| альфа | D +70° (c = 1 in THF, 22°) |
| Температура кипения | 630.87°C (rough estimate) |
| плотность | 1.0967 (rough estimate) |
| показатель преломления | 1.7800 (estimate) |
| температура хранения | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| растворимость | DMSO (Slightly, Heated), Methanol (Slightly, Heated), THF (Slightly, Heated, Soncited) |
| пка | 10.14±0.20(Predicted) |
| форма | Solid |
| цвет | White to Off-White |
| Справочник по базе данных CAS | 55726-47-1(CAS DataBase Reference) |
| FDA UNII | 9YVR68W306 |
Эноцитабин химические свойства, назначение, производство
Описание
Enocitabine (NSC-239336, BHAC) is an antileukemic agent closely related to cytarabine. It appears more resistant to deamination than cytarabine, thus allowing greater in vivo phosphorylation into an active cytotoxic metabolite. Enocitabine is lipophilic, but the drug does not enter the cerebrospinal fluid and is concentrated in the bone marrow and red blood cells. It can be administered orally and appears to be more effective than the parent compound in preclinical models.Химические свойства
Crystalline SolidЭноцитабин поставщик
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